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Deficit in Motor Skill Consolidation-Dependent Synaptic Plasticity at Motor Cortex to Dorsolateral Striatum Synapses in a Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disease notably characterized by progressive motor symptoms. Although the loss of medium spiny neurons (MSNs) in the striatum has been associated with motor deficits, premanifest patients already present cognitive deficiencies and show early signs of...

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Detalles Bibliográficos
Autores principales: Glangetas, Christelle, Espinosa, Pedro, Bellone, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139551/
https://www.ncbi.nlm.nih.gov/pubmed/32144144
http://dx.doi.org/10.1523/ENEURO.0297-19.2020

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