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c-MYC Expression Is a Possible Keystone in the Colorectal Cancer Resistance to EGFR Inhibitors

Alterations in the transcriptional factor c-MYC could be involved in the anti-EGFR resistance in metastatic colorectal cancer (mCRC). The c-MYC expression was evaluated in 121 RAS and BRAF wild-type mCRC before treatment with anti-EGFR+Folfiri therapy and in 33 subsequent metastases collected during...

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Detalles Bibliográficos
Autores principales:	Strippoli, Antonia, Cocomazzi, Alessandra, Basso, Michele, Cenci, Tonia, Ricci, Riccardo, Pierconti, Francesco, Cassano, Alessandra, Fiorentino, Vincenzo, Barone, Carlo, Bria, Emilio, Ricci-Vitiani, Lucia, Tortora, Giampaolo, Larocca, Luigi Maria, Martini, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139615/ https://www.ncbi.nlm.nih.gov/pubmed/32164324 http://dx.doi.org/10.3390/cancers12030638

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