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The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of α-Synuclein Amyloid Fibril Formation
The amyloid fibril formation by [Formula: see text]-synuclein is a hallmark of various neurodegenerative disorders, most notably Parkinson’s disease. Epigallocatechin gallate (EGCG) has been reported to be an efficient inhibitor of amyloid formation by numerous proteins, among them [Formula: see tex...
Autores principales: | Sternke-Hoffmann, Rebecca, Peduzzo, Alessia, Bolakhrif, Najoua, Haas, Rainer, Buell, Alexander K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139648/ https://www.ncbi.nlm.nih.gov/pubmed/32183378 http://dx.doi.org/10.3390/ijms21061995 |
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