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Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species
In recent years, epidemiological studies have shown that food is a very powerful means for maintaining a state of well-being and for health prevention. Many degenerative, autoimmune and neoplastic diseases are related to nutrition and the nutrient–organism interaction could define the balance betwee...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139678/ https://www.ncbi.nlm.nih.gov/pubmed/32178382 http://dx.doi.org/10.3390/ijms21061936 |
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author | Calvani, Maura Pasha, Amada Favre, Claudio |
author_facet | Calvani, Maura Pasha, Amada Favre, Claudio |
author_sort | Calvani, Maura |
collection | PubMed |
description | In recent years, epidemiological studies have shown that food is a very powerful means for maintaining a state of well-being and for health prevention. Many degenerative, autoimmune and neoplastic diseases are related to nutrition and the nutrient–organism interaction could define the balance between health and disease. Nutrients and dietary components influence epigenetic phenomena and modify drugs response; therefore, these food–host interactions can influence the individual predisposition to disease and its potential therapeutic response. Do nutraceuticals have positive or negative effects during chemotherapy? The use of nutraceutical supplements in cancer patients is a controversial debate without a definitive conclusion to date. During cancer treatment, patients take nutraceuticals to alleviate drug toxicity and improve long-term results. Some nutraceuticals may potentiate the effect of cytotoxic chemotherapy by inducing cell growth arrest, cell differentiation, and alteration of the redox state of cells, but in some cases, high levels of them may interfere with the effectiveness of chemotherapy, making cancer cells less reactive to chemotherapy. In this review, we highlighted the emerging opinions and data on the pros and cons on the use of nutraceutical supplements during chemotherapy. |
format | Online Article Text |
id | pubmed-7139678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71396782020-04-10 Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species Calvani, Maura Pasha, Amada Favre, Claudio Int J Mol Sci Review In recent years, epidemiological studies have shown that food is a very powerful means for maintaining a state of well-being and for health prevention. Many degenerative, autoimmune and neoplastic diseases are related to nutrition and the nutrient–organism interaction could define the balance between health and disease. Nutrients and dietary components influence epigenetic phenomena and modify drugs response; therefore, these food–host interactions can influence the individual predisposition to disease and its potential therapeutic response. Do nutraceuticals have positive or negative effects during chemotherapy? The use of nutraceutical supplements in cancer patients is a controversial debate without a definitive conclusion to date. During cancer treatment, patients take nutraceuticals to alleviate drug toxicity and improve long-term results. Some nutraceuticals may potentiate the effect of cytotoxic chemotherapy by inducing cell growth arrest, cell differentiation, and alteration of the redox state of cells, but in some cases, high levels of them may interfere with the effectiveness of chemotherapy, making cancer cells less reactive to chemotherapy. In this review, we highlighted the emerging opinions and data on the pros and cons on the use of nutraceutical supplements during chemotherapy. MDPI 2020-03-12 /pmc/articles/PMC7139678/ /pubmed/32178382 http://dx.doi.org/10.3390/ijms21061936 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Calvani, Maura Pasha, Amada Favre, Claudio Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title | Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title_full | Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title_fullStr | Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title_full_unstemmed | Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title_short | Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen Species |
title_sort | nutraceutical boom in cancer: inside the labyrinth of reactive oxygen species |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139678/ https://www.ncbi.nlm.nih.gov/pubmed/32178382 http://dx.doi.org/10.3390/ijms21061936 |
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