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Globular Adiponectin Inhibits Breast Cancer Cell Growth through Modulation of Inflammasome Activation: Critical Role of Sestrin2 and AMPK Signaling

Adiponectin, an adipokine predominantly derived from adipose tissue, exhibits potent antitumor properties in breast cancer cells. However, its mechanisms of action remain elusive. Inflammasomes—intracellular multimeric protein complexes—modulate cancer cell growth in a complicated manner, as well as...

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Detalles Bibliográficos
Autores principales: Pham, Duc-Vinh, Raut, Pawan Kumar, Pandit, Mahesh, Chang, Jae-Hoon, Katila, Nikita, Choi, Dong-Young, Jeong, Jee-Heon, Park, Pil-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139717/
https://www.ncbi.nlm.nih.gov/pubmed/32155890
http://dx.doi.org/10.3390/cancers12030613