Serine Biosynthesis Pathway Supports MYC–miR-494–EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells

Burkitt lymphoma (BL) is a rapidly growing tumor, characterized by high anabolic requirements. The MYC oncogene plays a central role in the pathogenesis of this malignancy, controlling genes involved in apoptosis, proliferation, and cellular metabolism. Serine biosynthesis pathway (SBP) couples glyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Białopiotrowicz, Emilia, Noyszewska-Kania, Monika, Kachamakova-Trojanowska, Neli, Łoboda, Agnieszka, Cybulska, Magdalena, Grochowska, Aleksandra, Kopczyński, Michał, Mikula, Michał, Prochorec-Sobieszek, Monika, Firczuk, Małgorzata, Graczyk-Jarzynka, Agnieszka, Zagożdżon, Radosław, Ząbek, Adam, Młynarz, Piotr, Dulak, Józef, Górniak, Patryk, Szydłowski, Maciej, Pyziak, Karolina, Martyka, Justyna, Sroka-Porada, Agnieszka, Jabłońska, Ewa, Polak, Anna, Kowalczyk, Piotr, Szumera-Ciećkiewicz, Anna, Chapuy, Bjoern, Rzymski, Tomasz, Brzózka, Krzysztof, Juszczyński, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139810/
https://www.ncbi.nlm.nih.gov/pubmed/32138178
http://dx.doi.org/10.3390/cancers12030580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139810/
https://www.ncbi.nlm.nih.gov/pubmed/32138178
http://dx.doi.org/10.3390/cancers12030580

Ejemplares similares