ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) stress generates reactive oxygen species (ROS) that induce apoptosis if left unabated. To limit oxidative insults, the ER stress PKR-like endoplasmic reticulum Kinase (PERK) has been reported to phosphorylate and activate nuclear factor erythroid 2-related factor 2 (NRF2)....

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Detalles Bibliográficos
Autores principales: Sarcinelli, Carmen, Dragic, Helena, Piecyk, Marie, Barbet, Virginie, Duret, Cédric, Barthelaix, Audrey, Ferraro-Peyret, Carole, Fauvre, Joelle, Renno, Toufic, Chaveroux, Cédric, Manié, Serge N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139862/
https://www.ncbi.nlm.nih.gov/pubmed/32121537
http://dx.doi.org/10.3390/cancers12030569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139862/
https://www.ncbi.nlm.nih.gov/pubmed/32121537
http://dx.doi.org/10.3390/cancers12030569

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