mTOR and STAT3 Pathway Hyper-Activation is Associated with Elevated Interleukin-6 Levels in Patients with Shwachman-Diamond Syndrome: Further Evidence of Lymphoid Lineage Impairment

Shwachman–Diamond syndrome (SDS) is a rare inherited bone marrow failure syndrome, resulting in neutropenia and a risk of myeloid neoplasia. A mutation in a ribosome maturation factor accounts for almost all of the cases. Lymphoid involvement in SDS has not been well characterized. We recently repor...

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Detalles Bibliográficos
Autores principales: Vella, Antonio, D’Aversa, Elisabetta, Api, Martina, Breveglieri, Giulia, Allegri, Marisole, Giacomazzi, Alice, Marinelli Busilacchi, Elena, Fabrizzi, Benedetta, Cestari, Tiziana, Sorio, Claudio, Bedini, Gloria, D’Amico, Giovanna, Bronte, Vincenzo, Poloni, Antonella, Benedetti, Antonio, Bovo, Chiara, Corey, Seth J., Borgatti, Monica, Cipolli, Marco, Bezzerri, Valentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139896/
https://www.ncbi.nlm.nih.gov/pubmed/32150944
http://dx.doi.org/10.3390/cancers12030597

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