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Claudin-12 Knockout Mice Demonstrate Reduced Proximal Tubule Calcium Permeability

The renal proximal tubule (PT) is responsible for the reabsorption of approximately 65% of filtered calcium, primarily via a paracellular pathway. However, which protein(s) contribute this paracellular calcium pore is not known. The claudin family of tight junction proteins confers permeability prop...

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Detalles Bibliográficos
Autores principales: Plain, Allein, Pan, Wanling, O’Neill, Deborah, Ure, Megan, Beggs, Megan R., Farhan, Maikel, Dimke, Henrik, Cordat, Emmanuelle, Alexander, R. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139911/
https://www.ncbi.nlm.nih.gov/pubmed/32197346
http://dx.doi.org/10.3390/ijms21062074

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