Cargando…
Biology and Therapeutic Targets of Colorectal Serrated Adenocarcinoma; Clues for a Histologically Based Treatment against an Aggressive Tumor
Serrated adenocarcinoma (SAC) is a tumor recognized by the WHO as a histological subtype accounting for around 9% of colorectal carcinomas. Compared to conventional carcinomas, SACs are characterized by a worse prognosis, weak development of the immune response, an active invasive front and a freque...
Autores principales: | Alburquerque-González, Begoña, López-Calderón, Fernando F., López-Abellán, María Dolores, Esteban-Gil, Ángel, García-Solano, José, Conesa-Zamora, Pablo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139914/ https://www.ncbi.nlm.nih.gov/pubmed/32183342 http://dx.doi.org/10.3390/ijms21061991 |
Ejemplares similares
-
Two histologically colorectal carcinomas subsets from the serrated pathway show different methylome signatures and diagnostic biomarkers
por: García-Solano, José, et al.
Publicado: (2018) -
Colorectal Adenocarcinoma with an Alternative Serrated Pathway
por: Eizuka, Makoto, et al.
Publicado: (2018) -
Methylome profiling reveals functions and genes which are differentially methylated in serrated compared to conventional colorectal carcinoma
por: Conesa-Zamora, Pablo, et al.
Publicado: (2015) -
ColPortal, an integrative multiomic platform for analysing epigenetic interactions in colorectal cancer
por: Esteban-Gil, Angel, et al.
Publicado: (2019) -
Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma
por: Stefanius, Karoliina, et al.
Publicado: (2011)