Cargando…

Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation

Alterations in the expression of glutamate/aspartate transporter (GLAST) have been associated with several neuropathological conditions including Alzheimer’s disease and epilepsy. However, the mechanisms by which GLAST expression is altered are poorly understood. Here we used a combination of pharma...

Descripción completa

Detalles Bibliográficos
Autores principales: Dematteis, Giulia, Restelli, Elena, Chiesa, Roberto, Aronica, Eleonora, Genazzani, Armando A, Lim, Dmitry, Tapella, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139922/
https://www.ncbi.nlm.nih.gov/pubmed/32210081
http://dx.doi.org/10.3390/ijms21062213