Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized (13)C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures

Non-invasive assessment of the biological aggressiveness of prostate cancer (PCa) is needed for men with localized disease. Hyperpolarized (HP) (13)C magnetic resonance (MR) spectroscopy is a powerful approach to image metabolism, specifically the conversion of HP [1-(13)C]pyruvate to [1-(13)C]lacta...

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Detalles Bibliográficos
Autores principales: Sriram, Renuka, Van Criekinge, Mark, DeLos Santos, Justin, Ahamed, Fayyaz, Qin, Hecong, Nolley, Rosalie, DeLos Santos, Romelyn, Tabatabai, Z. Laura, Bok, Robert A., Keshari, Kayvan R., Vigneron, Daniel B., Peehl, Donna M., Kurhanewicz, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139946/
https://www.ncbi.nlm.nih.gov/pubmed/32110965
http://dx.doi.org/10.3390/cancers12030537

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