The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfa...

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Detalles Bibliográficos
Autores principales: Andreeva, Antonina, Kulesha, Eugene, Gough, Julian, Murzin, Alexey G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139981/
https://www.ncbi.nlm.nih.gov/pubmed/31724711
http://dx.doi.org/10.1093/nar/gkz1064
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author Andreeva, Antonina
Kulesha, Eugene
Gough, Julian
Murzin, Alexey G
author_facet Andreeva, Antonina
Kulesha, Eugene
Gough, Julian
Murzin, Alexey G
author_sort Andreeva, Antonina
collection PubMed
description The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfamilies with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. The database is accessible from http://scop.mrc-lmb.cam.ac.uk.
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spelling pubmed-71399812020-04-13 The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures Andreeva, Antonina Kulesha, Eugene Gough, Julian Murzin, Alexey G Nucleic Acids Res NAR Breakthrough Article The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfamilies with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. The database is accessible from http://scop.mrc-lmb.cam.ac.uk. Oxford University Press 2020-01-08 2019-11-14 /pmc/articles/PMC7139981/ /pubmed/31724711 http://dx.doi.org/10.1093/nar/gkz1064 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle NAR Breakthrough Article
Andreeva, Antonina
Kulesha, Eugene
Gough, Julian
Murzin, Alexey G
The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title_full The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title_fullStr The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title_full_unstemmed The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title_short The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
title_sort scop database in 2020: expanded classification of representative family and superfamily domains of known protein structures
topic NAR Breakthrough Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139981/
https://www.ncbi.nlm.nih.gov/pubmed/31724711
http://dx.doi.org/10.1093/nar/gkz1064
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