Cargando…
Recellularized Colorectal Cancer Patient-Derived Scaffolds as In Vitro Pre-Clinical 3D Model for Drug Screening
Colorectal cancer (CRC) shows highly ineffective therapeutic management. An urgent unmet need is the random assignment to adjuvant chemotherapy of high-risk stage II and stage III CRC patients without any predictive factor of efficacy. In the field of drug discovery, a critical step is the preclinic...
Autores principales: | Sensi, Francesca, D’Angelo, Edoardo, Piccoli, Martina, Pavan, Piero, Mastrotto, Francesca, Caliceti, Paolo, Biccari, Andrea, Corallo, Diana, Urbani, Luca, Fassan, Matteo, Spolverato, Gaya, Riello, Pietro, Pucciarelli, Salvatore, Agostini, Marco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140024/ https://www.ncbi.nlm.nih.gov/pubmed/32183226 http://dx.doi.org/10.3390/cancers12030681 |
Ejemplares similares
-
The Study of the Extracellular Matrix in Chronic Inflammation: A Way to Prevent Cancer Initiation?
por: Marangio, Asia, et al.
Publicado: (2022) -
Patient-Derived Scaffolds of Colorectal Cancer Metastases as an Organotypic 3D Model of the Liver Metastatic Microenvironment
por: D’Angelo, Edoardo, et al.
Publicado: (2020) -
Optimization of Biomimetic, Leukocyte-Mimicking Nanovesicles for Drug Delivery Against Colorectal Cancer Using a Design of Experiment Approach
por: Rampado, Riccardo, et al.
Publicado: (2022) -
An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid
por: Moracci, Laura, et al.
Publicado: (2022) -
Tumor Cells and the Extracellular Matrix Dictate the Pro-Tumoral Profile of Macrophages in CRC
por: Coletta, Sara, et al.
Publicado: (2021)