Cargando…

Changes in DNA Damage Response Markers with Treatment in Advanced Ovarian Cancer

Ovarian cancer (OC) is sensitive to upfront chemotherapy, which is likely attributable to defects in DNA damage repair (DDR). Unfortunately, patients relapse and the evolution of DDR competency are poorly described. We examined the expression of proposed effectors in homologous recombination (HR: RA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kubelac, Paul, Genestie, Catherine, Auguste, Aurelie, Mesnage, Soizick, Le Formal, Audrey, Pautier, Patricia, Gouy, Sebastien, Morice, Philippe, Bentivegna, Enrica, Maulard, Amandine, Adam, Julien, Achimas-Cadariu, Patriciu, Leary, Alexandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140046/ https://www.ncbi.nlm.nih.gov/pubmed/32192091 http://dx.doi.org/10.3390/cancers12030707

Ejemplares similares

Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer
por: Leary, Alexandra, et al.
Publicado: (2020)

Clinical utility of SMARCA4 testing by immunohistochemistry in rare ovarian tumours
por: Genestie, Catherine, et al.
Publicado: (2019)

Staging surgery in early-stage ovarian mucinous tumors according to expansile and infiltrative types
por: Gouy, Sebastien, et al.
Publicado: (2017)

Is uterine preservation combined with bilateral salpingo-oophorectomy to promote subsequent fertility safe in infiltrative mucinous ovarian cancer?
por: Gouy, Sebastien, et al.
Publicado: (2017)

Cervical Cancer and Fertility-Sparing Treatment
por: Zaccarini, François, et al.
Publicado: (2021)

False negative rate at (18)F-FDG PET/CT in para-aortic lymphnode involvement in patients with locally advanced cervical cancer: impact of PET technology
por: Gouy, Sebastien, et al.
Publicado: (2021)

Evolutionary perspectives, heterogeneity and ovarian cancer: a complicated tale from past to present
por: Achimas-Cadariu, Patriciu, et al.
Publicado: (2022)

Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis
por: Auguste, Aurélie, et al.
Publicado: (2020)

Circulating Tumor DNA from Ascites as an alternative to tumor sampling for genomic profiling in ovarian cancer patients
por: Kfoury, Maria, et al.
Publicado: (2023)

Antiproliferative Ruthenium Complexes Containing Curcuminoid Ligands Tested In Vitro on Human Ovarian Tumor Cell Line A2780, towards Their Capability to Modulate the NF-κBTranscription Factor, FGF-2 Growth Factor, and MMP-9 Pathway
por: Leskovská, Janka, et al.
Publicado: (2022)

Comprehensive Analysis of the Expression of Key Genes Related to Hippo Signaling and Their Prognosis Impact in Ovarian Cancer
por: Kubelac, Paul, et al.
Publicado: (2021)

Impact of Hormone Replacement Therapy on the Overall Survival and Progression Free Survival of Ovarian Cancer Patients: A Systematic Review and Meta-Analysis
por: Achimaș-Cadariu, Patriciu Andrei, et al.
Publicado: (2023)

Unusual skin metastasis in a patient with recurrent micropapillary serous ovarian carcinoma – a case report and review of the literature
por: ACHIMAŞ-CADARIU, PATRICIU, et al.
Publicado: (2015)

Analysis of Systemic Inflammatory Factors and Survival Outcomes in Endometrial Cancer Patients Staged I-III FIGO and Treated with Postoperative External Radiotherapy
por: Holub, Katarzyna, et al.
Publicado: (2020)

Current Standards in the Management of Early and Locally Advanced Cervical Cancer: Update on the Benefit of Neoadjuvant/Adjuvant Strategies
por: Zhou, Yuedan, et al.
Publicado: (2022)

A Comparative Study between 18F-FDG PET/CT and Conventional Imaging in the Evaluation of Progressive Disease and Recurrence in Ovarian Carcinoma
por: Rusu, George, et al.
Publicado: (2021)

Fertility preservation in Hodgkin’s lymphoma patients that undergo targeted molecular therapies: an important step forward from the chemotherapy era
por: Traila, Alexandra, et al.
Publicado: (2018)

The role of medical registries, potential applications and limitations
por: Pop, Bogdan, et al.
Publicado: (2019)

Combined Tumor-Based BRCA1/2 and TP53 Mutation Testing in Ovarian Cancer
por: Borcoman, Edith, et al.
Publicado: (2023)

CT-guided procedures: an initial experience
por: ROMAN, ANDREI, et al.
Publicado: (2018)

Homologous recombination deficiency (HRD) testing on cell-free tumor DNA from peritoneal fluid
por: Roussel-Simonin, Cyril, et al.
Publicado: (2023)

The Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human Cancers
por: BOCHIS, OVIDIU VASILE, et al.
Publicado: (2015)

Adenosquamous Carcinoma of the Uterine Cervix – Impact of Histology on Clinical Management
por: Yordanov, Angel, et al.
Publicado: (2021)

Predictors of limph node metastasis in endometrial cancer
por: IGNAT, FLORIN LAURENTIU, et al.
Publicado: (2013)

miRNA expression profiling in formalin-fixed paraffin-embedded endometriosis and ovarian cancer samples
por: Braicu, Ovidiu-Leonard, et al.
Publicado: (2017)

Plasma miR-200b in ovarian carcinoma patients: distinct pattern of pre/post-treatment variation compared to CA-125 and potential for prediction of progression-free survival
por: Kapetanakis, Nikiforos-Ioannis, et al.
Publicado: (2015)

p53 siRNA - a therapeutic tool with significant implication in the modulation of apoptosis and angiogenic pathways
por: BRAICU, OVIDIU, et al.
Publicado: (2015)

Ovarian Real-World International Consortium (ORWIC): A multicentre, real-world analysis of epithelial ovarian cancer treatment and outcomes
por: Cheeseman, Sue, et al.
Publicado: (2023)

Novel Phenothiazine-Bridged Porphyrin-(Hetero)aryl dyads: Synthesis, Optical Properties, In Vitro Cytotoxicity and Staining of Human Ovarian Tumor Cell Lines
por: Molnar, Eva, et al.
Publicado: (2020)

The role of ketamine in the treatment of chronic cancer pain
por: ZGAIA, ARMEANA OLIMPIA, et al.
Publicado: (2015)

Cytotoxicity Evaluation of Unmodified Paddlewheel Dirhodium(II,II)-Acetate/-Formamidinate Complexes and Their Axially Modified Low-Valent Metallodendrimers
por: de Doncker, Stephen, et al.
Publicado: (2023)

Neutrophilia in locally advanced cervical cancer: A novel biomarker for image-guided adaptive brachytherapy?
por: Escande, Alexandre, et al.
Publicado: (2016)

Influence of Clinical and Surgical Factors on Uterine Carcinosarcoma Survival
por: Gracia, Myriam, et al.
Publicado: (2023)

SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer
por: Moisoiu, Vlad, et al.
Publicado: (2019)

Dual Targeted Therapy with p53 siRNA and Epigallocatechingallate in a Triple Negative Breast Cancer Cell Model
por: Braicu, Cornelia, et al.
Publicado: (2015)

Clinical and pathological implications of miRNA in bladder cancer
por: Braicu, Cornelia, et al.
Publicado: (2015)

What to do when nothing else is left to be done - metastatic non-HPV vulvar squamous cell carcinoma with multiple lines of chemotherapy
por: Stana, Mihaela Mărioara, et al.
Publicado: (2021)

PSA Based Biomarkers, Imagistic Techniques and Combined Tests for a Better Diagnostic of Localized Prostate Cancer
por: Munteanu, Vlad Cristian, et al.
Publicado: (2020)

Prognostic factors for in-transit metastasis in patients with malignant melanoma
por: Gâta, Vlad Alexandru, et al.
Publicado: (2022)

The development of scientific reasoning in medical education: a psychological perspective
por: BARZ, DANIELA LUMINITA, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5i2gte5n3gplb40rbknis56uu7