Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer

The long-term efficacy of the Epidermal Growth Factor Receptor (EGFR)-targeted antibody cetuximab in advanced colorectal cancer (CRC) patients is limited by the emergence of drug-resistant (persister) cells. Recent studies in other cancer types have shown that cells surviving initial treatment with...

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Detalles Bibliográficos
Autores principales: Lorenzato, Annalisa, Magrì, Alessandro, Matafora, Vittoria, Audrito, Valentina, Arcella, Pamela, Lazzari, Luca, Montone, Monica, Lamba, Simona, Deaglio, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Bachi, Angela, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140052/
https://www.ncbi.nlm.nih.gov/pubmed/32183295
http://dx.doi.org/10.3390/cancers12030685

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