The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas

Type 2 deiodinase (D2), the principal activator of thyroid hormone (TH) signaling in target tissues, is expressed in cutaneous squamous cell carcinomas (SCCs) during late tumorigenesis, and its repression attenuates the invasiveness and metastatic spread of SCC. Although D2 plays multiple roles in c...

Descripción completa

Detalles Bibliográficos
Autores principales: Nappi, Annarita, Di Cicco, Emery, Miro, Caterina, Cicatiello, Annunziata Gaetana, Sagliocchi, Serena, Mancino, Giuseppina, Ambrosio, Raffaele, Luongo, Cristina, Di Girolamo, Daniela, De Stefano, Maria Angela, Porcelli, Tommaso, Stornaiuolo, Mariano, Dentice, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140064/
https://www.ncbi.nlm.nih.gov/pubmed/32197405
http://dx.doi.org/10.3390/cancers12030715

Ejemplares similares

Ejemplares similares