Inhibiting WNT Ligand Production for Improved Immune Recognition in the Ovarian Tumor Microenvironment

In ovarian cancer, upregulation of the Wnt/β–catenin pathway leads to chemoresistance and correlates with T cell exclusion from the tumor microenvironment (TME). Our objectives were to validate these findings in an independent cohort of ovarian cancer subjects and determine whether inhibiting the Wn...

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Detalles Bibliográficos
Autores principales: Goldsberry, Whitney N., Meza-Perez, Selene, Londoño, Angelina I., Katre, Ashwini A., Mott, Bryan T., Roane, Brandon M., Goel, Nidhi, Wall, Jaclyn A., Cooper, Sara J., Norian, Lyse A., Randall, Troy D., Birrer, Michael J., Arend, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140065/
https://www.ncbi.nlm.nih.gov/pubmed/32213921
http://dx.doi.org/10.3390/cancers12030766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140065/
https://www.ncbi.nlm.nih.gov/pubmed/32213921
http://dx.doi.org/10.3390/cancers12030766

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