Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics

Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a surveillance pathway used by cells to control the quality mRNAs and to fine-tune transcript abundance. NMD plays an important role in cell cycle regulation, cell viability, DNA damage response, while also serving as a barrier to virus infection...

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Detalles Bibliográficos
Autores principales: Pawlicka, Kamila, Kalathiya, Umesh, Alfaro, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140085/
https://www.ncbi.nlm.nih.gov/pubmed/32213869
http://dx.doi.org/10.3390/cancers12030765

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