Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy

Receptor tyrosine kinases (RTKs) are key regulatory signaling proteins governing cancer cell growth and metastasis. During the last two decades, several molecules targeting RTKs were used in oncology as a first or second line therapy in different types of cancer. However, their effectiveness is limi...

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Detalles Bibliográficos
Autores principales: Pottier, Charles, Fresnais, Margaux, Gilon, Marie, Jérusalem, Guy, Longuespée, Rémi, Sounni, Nor Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140093/
https://www.ncbi.nlm.nih.gov/pubmed/32244867
http://dx.doi.org/10.3390/cancers12030731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140093/
https://www.ncbi.nlm.nih.gov/pubmed/32244867
http://dx.doi.org/10.3390/cancers12030731

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