Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability

A hallmark of human cancer is global DNA hypomethylation (GDHO), but the mechanisms accounting for this defect and its pathological consequences have not been investigated in human epithelial ovarian cancer (EOC). In EOC, GDHO was associated with advanced disease and reduced overall and disease-free...

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Detalles Bibliográficos
Autores principales: Zhang, Wa, Klinkebiel, David, Barger, Carter J., Pandey, Sanjit, Guda, Chittibabu, Miller, Austin, Akers, Stacey N., Odunsi, Kunle, Karpf, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140107/
https://www.ncbi.nlm.nih.gov/pubmed/32213861
http://dx.doi.org/10.3390/cancers12030764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140107/
https://www.ncbi.nlm.nih.gov/pubmed/32213861
http://dx.doi.org/10.3390/cancers12030764

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