Mesenchymal Stem Cell-Specific and Preosteoblast-Specific Ablation of TSC1 in Mice Lead to Severe and Slight Spinal Dysplasia, Respectively

BACKGROUND: TSC1-related signaling plays a pivotal role in intramembranous and endochondral ossification processes during skeletogenesis. This study was aimed at determining the significance of the TSC1 gene at different stages of spinal development. Materials and Methods. TSC1-floxed mice (TSC1(flo...

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Detalles Bibliográficos
Autores principales: Yang, Cheng, Liao, Jianwen, Lai, Pinglin, Huang, Hai, Fan, Shicai, Chen, Yuhui, Bai, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140121/
https://www.ncbi.nlm.nih.gov/pubmed/32309432
http://dx.doi.org/10.1155/2020/4572687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140121/
https://www.ncbi.nlm.nih.gov/pubmed/32309432
http://dx.doi.org/10.1155/2020/4572687

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