Yellow fever vector live-virus vaccines: West Nile virus vaccine development

By combining molecular-biological techniques with our increased understanding of the effect of gene sequence modification on viral function, yellow fever 17D, a positive-strand RNA virus vaccine, has been manipulated to induce a protective immune response against viruses of the same family (e.g. Jap...

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Detalles Bibliográficos
Autores principales: Arroyo, Juan, Miller, Charles A, Catalan, John, Monath, Thomas P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140174/
https://www.ncbi.nlm.nih.gov/pubmed/11516995
http://dx.doi.org/10.1016/S1471-4914(01)02048-2
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author Arroyo, Juan
Miller, Charles A
Catalan, John
Monath, Thomas P
author_facet Arroyo, Juan
Miller, Charles A
Catalan, John
Monath, Thomas P
author_sort Arroyo, Juan
collection PubMed
description By combining molecular-biological techniques with our increased understanding of the effect of gene sequence modification on viral function, yellow fever 17D, a positive-strand RNA virus vaccine, has been manipulated to induce a protective immune response against viruses of the same family (e.g. Japanese encephalitis and dengue viruses). Triggered by the emergence of West Nile virus infections in the New World afflicting humans, horses and birds, the success of this recombinant technology has prompted the rapid development of a live-virus attenuated candidate vaccine against West Nile virus.
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spelling pubmed-71401742020-04-08 Yellow fever vector live-virus vaccines: West Nile virus vaccine development Arroyo, Juan Miller, Charles A Catalan, John Monath, Thomas P Trends Mol Med Article By combining molecular-biological techniques with our increased understanding of the effect of gene sequence modification on viral function, yellow fever 17D, a positive-strand RNA virus vaccine, has been manipulated to induce a protective immune response against viruses of the same family (e.g. Japanese encephalitis and dengue viruses). Triggered by the emergence of West Nile virus infections in the New World afflicting humans, horses and birds, the success of this recombinant technology has prompted the rapid development of a live-virus attenuated candidate vaccine against West Nile virus. Elsevier Science Ltd. 2001-08-01 2001-08-13 /pmc/articles/PMC7140174/ /pubmed/11516995 http://dx.doi.org/10.1016/S1471-4914(01)02048-2 Text en Copyright © 2001 Elsevier Science Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Arroyo, Juan
Miller, Charles A
Catalan, John
Monath, Thomas P
Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title_full Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title_fullStr Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title_full_unstemmed Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title_short Yellow fever vector live-virus vaccines: West Nile virus vaccine development
title_sort yellow fever vector live-virus vaccines: west nile virus vaccine development
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140174/
https://www.ncbi.nlm.nih.gov/pubmed/11516995
http://dx.doi.org/10.1016/S1471-4914(01)02048-2
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