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Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache

Encephalitis is often caused by viral infections and can affect various brain regions. The clinical symptoms are highly variable. Oligosymptomatic cerebral infections may remain undetected but there are also cases with very severe symptoms (e.g. paralysis, convulsions). This article presents the cas...

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Autores principales: Doberentz, E., Kuchelmeister, K., Drexler, F., Goeke, F., Madea, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140227/
https://www.ncbi.nlm.nih.gov/pubmed/32288295
http://dx.doi.org/10.1007/s00194-012-0823-z
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author Doberentz, E.
Kuchelmeister, K.
Drexler, F.
Goeke, F.
Madea, B.
author_facet Doberentz, E.
Kuchelmeister, K.
Drexler, F.
Goeke, F.
Madea, B.
author_sort Doberentz, E.
collection PubMed
description Encephalitis is often caused by viral infections and can affect various brain regions. The clinical symptoms are highly variable. Oligosymptomatic cerebral infections may remain undetected but there are also cases with very severe symptoms (e.g. paralysis, convulsions). This article presents the case of an 8-year-old girl who suffered from headaches and vomiting for several days following a harmless fall with impact on the back of the head. The health condition decreased rapidly and 7 days after the fall the girl was presented to a children’s hospital. After a further foudroyant course of the disease the girl was hospitalized 2 days later. Resuscitation became necessary due to convulsions and pulmonary obstruction. Cranial computed tomography (cCT) revealed temporal hypodense areas and local edema. Cardiac echocardiography revealed a decreased left ventricular pump function so that encephalitis and myocarditis were suspected. Despite antiviral and antibiotic therapy the girl died 4 days after admission due to intravital brain death and multiorgan failure. This cause of death was confirmed by forensic autopsy. The fall had not led to any intracranial injury and predisposing diseases were not found. Histological examination revealed necrotizing brainstem encephalitis.
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spelling pubmed-71402272020-04-08 Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache Doberentz, E. Kuchelmeister, K. Drexler, F. Goeke, F. Madea, B. Rechtsmedizin (Berl) Kasuistiken Encephalitis is often caused by viral infections and can affect various brain regions. The clinical symptoms are highly variable. Oligosymptomatic cerebral infections may remain undetected but there are also cases with very severe symptoms (e.g. paralysis, convulsions). This article presents the case of an 8-year-old girl who suffered from headaches and vomiting for several days following a harmless fall with impact on the back of the head. The health condition decreased rapidly and 7 days after the fall the girl was presented to a children’s hospital. After a further foudroyant course of the disease the girl was hospitalized 2 days later. Resuscitation became necessary due to convulsions and pulmonary obstruction. Cranial computed tomography (cCT) revealed temporal hypodense areas and local edema. Cardiac echocardiography revealed a decreased left ventricular pump function so that encephalitis and myocarditis were suspected. Despite antiviral and antibiotic therapy the girl died 4 days after admission due to intravital brain death and multiorgan failure. This cause of death was confirmed by forensic autopsy. The fall had not led to any intracranial injury and predisposing diseases were not found. Histological examination revealed necrotizing brainstem encephalitis. Springer-Verlag 2012-05-10 2012 /pmc/articles/PMC7140227/ /pubmed/32288295 http://dx.doi.org/10.1007/s00194-012-0823-z Text en © Springer-Verlag 2012 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Kasuistiken
Doberentz, E.
Kuchelmeister, K.
Drexler, F.
Goeke, F.
Madea, B.
Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title_full Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title_fullStr Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title_full_unstemmed Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title_short Hirnstammenzephalitis eines 8-jährigen Mädchens: Seltene Todesursache
title_sort hirnstammenzephalitis eines 8-jährigen mädchens: seltene todesursache
topic Kasuistiken
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140227/
https://www.ncbi.nlm.nih.gov/pubmed/32288295
http://dx.doi.org/10.1007/s00194-012-0823-z
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