Regulation of Necroptosis by Phospholipids and Sphingolipids

Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggest...

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Detalles Bibliográficos
Autores principales: Zhang, Xuewei, Matsuda, Masaya, Yaegashi, Nobuo, Nabe, Takeshi, Kitatani, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140401/
https://www.ncbi.nlm.nih.gov/pubmed/32151027
http://dx.doi.org/10.3390/cells9030627
Descripción
Sumario:Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggests a key role for lipidic molecules in the regulation of necroptosis. The purpose of this mini-review is to outline the regulation of necroptosis by sphingolipids and phospholipids.

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