Regulation of Necroptosis by Phospholipids and Sphingolipids

Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggest...

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Autores principales: Zhang, Xuewei, Matsuda, Masaya, Yaegashi, Nobuo, Nabe, Takeshi, Kitatani, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140401/
https://www.ncbi.nlm.nih.gov/pubmed/32151027
http://dx.doi.org/10.3390/cells9030627
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author Zhang, Xuewei
Matsuda, Masaya
Yaegashi, Nobuo
Nabe, Takeshi
Kitatani, Kazuyuki
author_facet Zhang, Xuewei
Matsuda, Masaya
Yaegashi, Nobuo
Nabe, Takeshi
Kitatani, Kazuyuki
author_sort Zhang, Xuewei
collection PubMed
description Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggests a key role for lipidic molecules in the regulation of necroptosis. The purpose of this mini-review is to outline the regulation of necroptosis by sphingolipids and phospholipids.
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spelling pubmed-71404012020-04-13 Regulation of Necroptosis by Phospholipids and Sphingolipids Zhang, Xuewei Matsuda, Masaya Yaegashi, Nobuo Nabe, Takeshi Kitatani, Kazuyuki Cells Review Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage kinase domain-like protein. Recent evidence suggests a key role for lipidic molecules in the regulation of necroptosis. The purpose of this mini-review is to outline the regulation of necroptosis by sphingolipids and phospholipids. MDPI 2020-03-05 /pmc/articles/PMC7140401/ /pubmed/32151027 http://dx.doi.org/10.3390/cells9030627 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Xuewei
Matsuda, Masaya
Yaegashi, Nobuo
Nabe, Takeshi
Kitatani, Kazuyuki
Regulation of Necroptosis by Phospholipids and Sphingolipids
title Regulation of Necroptosis by Phospholipids and Sphingolipids
title_full Regulation of Necroptosis by Phospholipids and Sphingolipids
title_fullStr Regulation of Necroptosis by Phospholipids and Sphingolipids
title_full_unstemmed Regulation of Necroptosis by Phospholipids and Sphingolipids
title_short Regulation of Necroptosis by Phospholipids and Sphingolipids
title_sort regulation of necroptosis by phospholipids and sphingolipids
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140401/
https://www.ncbi.nlm.nih.gov/pubmed/32151027
http://dx.doi.org/10.3390/cells9030627
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