Motor Neuron Generation from iPSCs from Identical Twins Discordant for Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder characterized by the loss of the upper and lower motor neurons. Approximately 10% of cases are caused by specific mutations in known genes, with the remaining cases having no known genetic link. As such, sporadic cases have...

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Detalles Bibliográficos
Autores principales: Seminary, Emily R., Santarriaga, Stephanie, Wheeler, Lynn, Mejaki, Marie, Abrudan, Jenica, Demos, Wendy, Zimmermann, Michael T., Urrutia, Raul A., Fee, Dominic, Barkhaus, Paul E., Ebert, Allison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140469/
https://www.ncbi.nlm.nih.gov/pubmed/32121108
http://dx.doi.org/10.3390/cells9030571

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