Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial

BACKGROUND: Preoperative chemoradiotherapy (PCRT) followed by surgery and adjuvant chemotherapy is the current standard treatment for stage II/III rectal cancer. However, radiotherapy in the pelvic area is commonly associated with complications such as anastomotic leakage, sexual dysfunction, and fe...

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Detalles Bibliográficos
Autores principales: Lee, Jii Bum, Kim, Han Sang, Jung, Inkyung, Shin, Sang Joon, Beom, Seung Hoon, Chang, Jee Suk, Koom, Woong Sub, Kim, Tae Il, Hur, Hyuk, Min, Byung Soh, Kim, Nam Kyu, Park, Sohee, Jeong, Seung-Yong, Baek, Jeong-Heum, Kim, Seon Hahn, Lim, Joon Seok, Lee, Kang Young, Ahn, Joong Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140505/
https://www.ncbi.nlm.nih.gov/pubmed/32264919
http://dx.doi.org/10.1186/s13063-020-04266-6

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