Cargando…

Hepatocyte Injury and Hepatic Stem Cell Niche in the Progression of Non-Alcoholic Steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by lipid accumulation in hepatocytes in the absence of excessive alcohol consumption. The global prevalence of NAFLD is constantly increasing. NAFLD is a disease spectrum comprising distinct stages with different prog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Overi, Diletta, Carpino, Guido, Franchitto, Antonio, Onori, Paolo, Gaudio, Eugenio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140508/ https://www.ncbi.nlm.nih.gov/pubmed/32131439 http://dx.doi.org/10.3390/cells9030590

Ejemplares similares

Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases
por: Safarikia, Samira, et al.
Publicado: (2020)

Effect of Calcium-Sulphate-Bicarbonate Water in a Murine Model of Non-Alcoholic Fatty Liver Disease: A Histopathology Study
por: Carpino, Guido, et al.
Publicado: (2022)

Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases
por: Overi, Diletta, et al.
Publicado: (2018)

Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration
por: Carpino, Guido, et al.
Publicado: (2016)

Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor
por: Franchitto, Antonio, et al.
Publicado: (2019)

Islet Regeneration and Pancreatic Duct Glands in Human and Experimental Diabetes
por: Overi, Diletta, et al.
Publicado: (2022)

Role of Hepatic Progenitor Cells in Nonalcoholic Fatty Liver Disease Development: Cellular Cross-Talks and Molecular Networks
por: Carpino, Guido, et al.
Publicado: (2013)

Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH
por: Del Ben, Maria, et al.
Publicado: (2018)

Role of Docosahexaenoic Acid Treatment in Improving Liver Histology in Pediatric Nonalcoholic Fatty Liver Disease
por: Nobili, Valerio, et al.
Publicado: (2014)

Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway
por: Carpino, Guido, et al.
Publicado: (2016)

Molecular Landscape and Therapeutic Strategies in Cholangiocarcinoma: An Integrated Translational Approach towards Precision Medicine
por: Casadio, Marco, et al.
Publicado: (2021)

Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells
por: Costantini, Daniele, et al.
Publicado: (2019)

Viral Hepatitis and Iron Dysregulation: Molecular Pathways and the Role of Lactoferrin
por: Mancinelli, Romina, et al.
Publicado: (2020)

Persistent biliary hypoxia and lack of regeneration are key mechanisms in the pathogenesis of posttransplant nonanastomotic strictures
por: de Jong, Iris E. M., et al.
Publicado: (2021)

PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress
por: Carpino, Guido, et al.
Publicado: (2017)

Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity
por: Kyritsi, Konstantina, et al.
Publicado: (2023)

Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
por: Vetuschi, Antonella, et al.
Publicado: (2022)

Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure
por: Carpino, Guido, et al.
Publicado: (2019)

Role of ductular reaction and ductular–canalicular junctions in identifying severe primary biliary cholangitis
por: Overi, Diletta, et al.
Publicado: (2022)

Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)
por: Li, Xinzhi, et al.
Publicado: (2022)

Morphological and Functional Heterogeneity of the Mouse Intrahepatic Biliary Epithelium
por: Glaser, Shannon, et al.
Publicado: (2009)

RNA-sequencing-based comparative analysis of human hepatic progenitor cells and their niche from alcoholic steatohepatitis livers
por: Ceulemans, An, et al.
Publicado: (2017)

Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis
por: Koh, Eun Hee, et al.
Publicado: (2021)

The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling
por: Mancinelli, Romina, et al.
Publicado: (2022)

Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis, and Angiogenesis in a Model of Cholangitis
por: Owen, Travis, et al.
Publicado: (2023)

Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma
por: Mancinelli, Romina, et al.
Publicado: (2020)

Caspase-11–Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis
por: Zhu, Yingwei, et al.
Publicado: (2021)

Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial
por: Della Corte, Claudia, et al.
Publicado: (2016)

Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells
por: Carnevale, Gianluca, et al.
Publicado: (2017)

The Emerging Role of Ferroptosis in Liver Cancers
por: Casini, Arianna, et al.
Publicado: (2022)

Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium
por: Casini, Arianna, et al.
Publicado: (2023)

Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice
por: Bao, Xinyu, et al.
Publicado: (2022)

Hepatocyte expressed chemerin-156 does not protect from experimental non-alcoholic steatohepatitis
por: Pohl, Rebekka, et al.
Publicado: (2022)

Hepatocytic Ballooning in Non-alcoholic Steatohepatitis: Bridging the Knowledge Gap and Charting Future Avenues
por: Singla, Tanvi, et al.
Publicado: (2023)

The Role of Epigenetic Changes in the Progression of Alcoholic Steatohepatitis
por: Kim, Hyeong Geug, et al.
Publicado: (2021)

Mast cells selectively target large cholangiocytes during biliary injury via H2HR‐mediated cAMP/pERK1/2 signaling
por: Zhou, Tianhao, et al.
Publicado: (2022)

Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model
por: Ceci, Ludovica, et al.
Publicado: (2022)

Roux-En Y Gastric Bypass Results in Long-Term Remission of Hepatocyte Apoptosis and Hepatic Histological Features of Non-alcoholic Steatohepatitis
por: Schneck, Anne-Sophie, et al.
Publicado: (2016)

Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice
por: Nan, YueMin, et al.
Publicado: (2010)

Peribiliary Glands Are Key in Regeneration of the Human Biliary Epithelium After Severe Bile Duct Injury
por: de Jong, Iris E.M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cesv4c7inm3uega6glm2gkf03h