FAK Deficiency in Bone Marrow Stromal Cells Alters Their Homeostasis and Drives Abnormal Proliferation and Differentiation of Haematopoietic Stem Cells

Emerging evidence indicates that in myelodysplastic syndromes (MDS), the bone marrow (BM) microenvironment may also contribute to the ineffective, malignant haematopoiesis in addition to the intrinsic abnormalities of haematopoietic stem precursor cells (HSPCs). The BM microenvironment influences ma...

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Detalles Bibliográficos
Autores principales: Wu, Yuenv, Campos, Lydia, Daguenet, Elisabeth, He, Zhiguo, Picot, Tiphanie, Tavernier-Tardy, Emmanuelle, Soglu, Gilbert, Guyotat, Denis, Aanei, Carmen-Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140540/
https://www.ncbi.nlm.nih.gov/pubmed/32155953
http://dx.doi.org/10.3390/cells9030646

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