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Gene expression responses to anti-tuberculous drugs in a whole blood model

BACKGROUND: There is a need for better tools to evaluate new or repurposed TB drugs. The whole blood bactericidal activity (WBA) assay has been advocated for this purpose. We investigated whether transcriptional responses in the WBA assay resemble TB responses in vivo, and whether the approach might...

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Detalles Bibliográficos
Autores principales:	Kwan, Philip Kam Weng, Lin, Wenwei, Naim, Ahmad Nazri Mohamed, Periaswamy, Balamurugan, De Sessions, Paola Florez, Hibberd, Martin L., Paton, Nicholas I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140558/ https://www.ncbi.nlm.nih.gov/pubmed/32264819 http://dx.doi.org/10.1186/s12866-020-01766-y

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