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Is T Cell Negative Selection a Learning Algorithm?
Our immune system can destroy most cells in our body, an ability that needs to be tightly controlled. To prevent autoimmunity, the thymic medulla exposes developing T cells to normal “self” peptides and prevents any responders from entering the bloodstream. However, a substantial number of self-reac...
Autores principales: | Wortel, Inge M. N., Keşmir, Can, de Boer, Rob J., Mandl, Judith N., Textor, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140671/ https://www.ncbi.nlm.nih.gov/pubmed/32168897 http://dx.doi.org/10.3390/cells9030690 |
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