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Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients

Interferon regulatory factors (IRFs) are emerging as the metabolic transcriptional regulators in obesity/type-2 diabetes (T2D). IRF5 is implicated with macrophage polarization toward the inflammatory M1-phenotype, nonetheless, changes in the adipose expression of IRF5 in T2D and relationship of thes...

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Detalles Bibliográficos
Autores principales: Sindhu, Sardar, Kochumon, Shihab, Thomas, Reeby, Bennakhi, Abdullah, Al-Mulla, Fahd, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140673/
https://www.ncbi.nlm.nih.gov/pubmed/32188105
http://dx.doi.org/10.3390/cells9030730