Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma

Resistance to radiotherapy (IR), with consequent disease recurrence, continues to limit the efficacy of contemporary anticancer treatment for patients with hepatocellular carcinoma (HCC), especially in late stage. Despite accruing evidence implicating the PI3K/AKT signaling pathway in cancer-promoti...

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Detalles Bibliográficos
Autores principales: Bamodu, Oluwaseun Adebayo, Chang, Hang-Lung, Ong, Jiann-Ruey, Lee, Wei-Hwa, Yeh, Chi-Tai, Tsai, Jo-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140693/
https://www.ncbi.nlm.nih.gov/pubmed/32197467
http://dx.doi.org/10.3390/cells9030746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140693/
https://www.ncbi.nlm.nih.gov/pubmed/32197467
http://dx.doi.org/10.3390/cells9030746

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