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Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis

Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing...

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Detalles Bibliográficos
Autores principales: Shin, Kyong-Oh, Ha, Dae Hyun, Kim, Jin Ock, Crumrine, Debra A., Meyer, Jason M., Wakefield, Joan S., Lee, Yerin, Kim, Bogyeong, Kim, Sungeun, Kim, Hyun-keun, Lee, Joon, Kwon, Hyuck Hoon, Park, Gyeong-Hun, Lee, Jun Ho, Lim, Jihye, Park, Sejeong, Elias, Peter M., Park, Kyungho, Yi, Yong Weon, Cho, Byong Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140723/
https://www.ncbi.nlm.nih.gov/pubmed/32164386
http://dx.doi.org/10.3390/cells9030680