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The FOXO’s Advantages of Being a Family: Considerations on Function and Evolution

The nematode Caenorhabditis elegans possesses a unique (with various isoforms) FOXO transcription factor DAF-16, which is notorious for its role in aging and its regulation by the insulin-PI3K-AKT pathway. In humans, five genes (including a protein-coding pseudogene) encode for FOXO transcription fa...

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Detalles Bibliográficos
Autor principal:	Schmitt-Ney, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140813/ https://www.ncbi.nlm.nih.gov/pubmed/32214027 http://dx.doi.org/10.3390/cells9030787

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