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Does DNA Methylation Matter in FSHD?

Facioscapulohumeral muscular dystrophy (FSHD) has been associated with the genetic and epigenetic molecular features of the CpG-rich D4Z4 repeat tandem array at 4q35. Reduced DNA methylation of D4Z4 repeats is considered part of the FSHD mechanism and has been proposed as a reliable marker in the FS...

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Detalles Bibliográficos
Autores principales:	Salsi, Valentina, Magdinier, Frédérique, Tupler, Rossella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140823/ https://www.ncbi.nlm.nih.gov/pubmed/32121044 http://dx.doi.org/10.3390/genes11030258

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