Inherited DNA Repair Gene Mutations in Men with Lethal Prostate Cancer

Germline variants in DNA repair genes are associated with aggressive prostate cancer (PrCa). The aim of this study was to characterize germline variants in DNA repair genes associated with lethal PrCa in Finnish and Swedish populations. Whole-exome sequencing was performed for 122 lethal and 60 unse...

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Detalles Bibliográficos
Autores principales: Rantapero, Tommi, Wahlfors, Tiina, Kähler, Anna, Hultman, Christina, Lindberg, Johan, Tammela, Teuvo L. J., Nykter, Matti, Schleutker, Johanna, Wiklund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140841/
https://www.ncbi.nlm.nih.gov/pubmed/32183364
http://dx.doi.org/10.3390/genes11030314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140841/
https://www.ncbi.nlm.nih.gov/pubmed/32183364
http://dx.doi.org/10.3390/genes11030314

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