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Characterization of a Homozygous Deletion of Steroid Hormone Biosynthesis Genes in Horse Chromosome 29 as a Risk Factor for Disorders of Sex Development and Reproduction

Disorders of sex development (DSD) and reproduction are not uncommon among horses, though knowledge about their molecular causes is sparse. Here we characterized a ~200 kb homozygous deletion in chromosome 29 at 29.7–29.9 Mb. The region contains AKR1C genes which function as ketosteroid reductases i...

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Detalles Bibliográficos
Autores principales:	Ghosh, Sharmila, Davis, Brian W., Rosengren, Maria, Jevit, Matthew J., Castaneda, Caitlin, Arnold, Carolyn, Jaxheimer, Jay, Love, Charles C., Varner, Dickson D., Lindgren, Gabriella, Wade, Claire M., Raudsepp, Terje
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140900/ https://www.ncbi.nlm.nih.gov/pubmed/32120906 http://dx.doi.org/10.3390/genes11030251

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