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OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma

Progression of actinic keratosis (AK) to cutaneous squamous cell carcinoma (cSCC) is rare. Most cases of AK remain as intraepidermal lesions, owing to the suppression of the epithelial-to-mesenchymal transition (EMT). Ovo-like transcriptional repressor 1 (OVOL1) and ovo-like zinc finger 2 (OVOL2) ar...

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Detalles Bibliográficos
Autores principales: Murata, Maho, Ito, Takamichi, Tanaka, Yuka, Yamamura, Kazuhiko, Furue, Kazuhisa, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141138/
https://www.ncbi.nlm.nih.gov/pubmed/32106476
http://dx.doi.org/10.3390/jcm9030618