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Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 Feb...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141223/ https://www.ncbi.nlm.nih.gov/pubmed/32183172 http://dx.doi.org/10.3390/jcm9030789 |
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author | Kuniya, Toshikazu |
author_facet | Kuniya, Toshikazu |
author_sort | Kuniya, Toshikazu |
collection | PubMed |
description | The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 February 2020. Taking into account the uncertainty due to the incomplete identification of infective population, we apply the well-known SEIR compartmental model for the prediction. By using a least-square-based method with Poisson noise, we estimate that the basic reproduction number for the epidemic in Japan is [Formula: see text] ([Formula: see text] CI, [Formula: see text] – [Formula: see text]) and the epidemic peak could possibly reach the early-middle summer. In addition, we obtain the following epidemiological insights: (1) the essential epidemic size is less likely to be affected by the rate of identification of the actual infective population; (2) the intervention has a positive effect on the delay of the epidemic peak; (3) intervention over a relatively long period is needed to effectively reduce the final epidemic size. |
format | Online Article Text |
id | pubmed-7141223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71412232020-04-10 Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 Kuniya, Toshikazu J Clin Med Article The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 February 2020. Taking into account the uncertainty due to the incomplete identification of infective population, we apply the well-known SEIR compartmental model for the prediction. By using a least-square-based method with Poisson noise, we estimate that the basic reproduction number for the epidemic in Japan is [Formula: see text] ([Formula: see text] CI, [Formula: see text] – [Formula: see text]) and the epidemic peak could possibly reach the early-middle summer. In addition, we obtain the following epidemiological insights: (1) the essential epidemic size is less likely to be affected by the rate of identification of the actual infective population; (2) the intervention has a positive effect on the delay of the epidemic peak; (3) intervention over a relatively long period is needed to effectively reduce the final epidemic size. MDPI 2020-03-13 /pmc/articles/PMC7141223/ /pubmed/32183172 http://dx.doi.org/10.3390/jcm9030789 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kuniya, Toshikazu Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title | Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title_full | Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title_fullStr | Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title_full_unstemmed | Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title_short | Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 |
title_sort | prediction of the epidemic peak of coronavirus disease in japan, 2020 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141223/ https://www.ncbi.nlm.nih.gov/pubmed/32183172 http://dx.doi.org/10.3390/jcm9030789 |
work_keys_str_mv | AT kuniyatoshikazu predictionoftheepidemicpeakofcoronavirusdiseaseinjapan2020 |