Cargando…

Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020

The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 Feb...

Descripción completa

Detalles Bibliográficos
Autor principal: Kuniya, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141223/
https://www.ncbi.nlm.nih.gov/pubmed/32183172
http://dx.doi.org/10.3390/jcm9030789
_version_ 1783519149922713600
author Kuniya, Toshikazu
author_facet Kuniya, Toshikazu
author_sort Kuniya, Toshikazu
collection PubMed
description The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 February 2020. Taking into account the uncertainty due to the incomplete identification of infective population, we apply the well-known SEIR compartmental model for the prediction. By using a least-square-based method with Poisson noise, we estimate that the basic reproduction number for the epidemic in Japan is [Formula: see text] ([Formula: see text] CI, [Formula: see text] – [Formula: see text]) and the epidemic peak could possibly reach the early-middle summer. In addition, we obtain the following epidemiological insights: (1) the essential epidemic size is less likely to be affected by the rate of identification of the actual infective population; (2) the intervention has a positive effect on the delay of the epidemic peak; (3) intervention over a relatively long period is needed to effectively reduce the final epidemic size.
format Online
Article
Text
id pubmed-7141223
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-71412232020-04-10 Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020 Kuniya, Toshikazu J Clin Med Article The first case of coronavirus disease 2019 (COVID-19) in Japan was reported on 15 January 2020 and the number of reported cases has increased day by day. The purpose of this study is to give a prediction of the epidemic peak for COVID-19 in Japan by using the real-time data from 15 January to 29 February 2020. Taking into account the uncertainty due to the incomplete identification of infective population, we apply the well-known SEIR compartmental model for the prediction. By using a least-square-based method with Poisson noise, we estimate that the basic reproduction number for the epidemic in Japan is [Formula: see text] ([Formula: see text] CI, [Formula: see text] – [Formula: see text]) and the epidemic peak could possibly reach the early-middle summer. In addition, we obtain the following epidemiological insights: (1) the essential epidemic size is less likely to be affected by the rate of identification of the actual infective population; (2) the intervention has a positive effect on the delay of the epidemic peak; (3) intervention over a relatively long period is needed to effectively reduce the final epidemic size. MDPI 2020-03-13 /pmc/articles/PMC7141223/ /pubmed/32183172 http://dx.doi.org/10.3390/jcm9030789 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kuniya, Toshikazu
Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title_full Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title_fullStr Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title_full_unstemmed Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title_short Prediction of the Epidemic Peak of Coronavirus Disease in Japan, 2020
title_sort prediction of the epidemic peak of coronavirus disease in japan, 2020
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141223/
https://www.ncbi.nlm.nih.gov/pubmed/32183172
http://dx.doi.org/10.3390/jcm9030789
work_keys_str_mv AT kuniyatoshikazu predictionoftheepidemicpeakofcoronavirusdiseaseinjapan2020