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Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy
The endothelin axis, recognized for its vasoconstrictive action, plays a central role in the pathology of pulmonary arterial hypertension (PAH). Treatment with approved endothelin receptor antagonists (ERAs), such as bosentan, ambrisentan, or macitentan, slow down PAH progression and relieves sympto...
Autores principales: | Enevoldsen, Frederik C., Sahana, Jayashree, Wehland, Markus, Grimm, Daniela, Infanger, Manfred, Krüger, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141375/ https://www.ncbi.nlm.nih.gov/pubmed/32197449 http://dx.doi.org/10.3390/jcm9030824 |
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