Cargando…

Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy

The endothelin axis, recognized for its vasoconstrictive action, plays a central role in the pathology of pulmonary arterial hypertension (PAH). Treatment with approved endothelin receptor antagonists (ERAs), such as bosentan, ambrisentan, or macitentan, slow down PAH progression and relieves sympto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Enevoldsen, Frederik C., Sahana, Jayashree, Wehland, Markus, Grimm, Daniela, Infanger, Manfred, Krüger, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141375/ https://www.ncbi.nlm.nih.gov/pubmed/32197449 http://dx.doi.org/10.3390/jcm9030824

Ejemplares similares

Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity
por: Melnik, Daniela, et al.
Publicado: (2020)

Breast Cancer Cells in Microgravity: New Aspects for Cancer Research
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2020)

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine
por: Sahana, Jayashree, et al.
Publicado: (2021)

The Vasoactive Mas Receptor in Essential Hypertension
por: Povlsen, Amalie L., et al.
Publicado: (2020)

The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure
por: Khalaf, David, et al.
Publicado: (2019)

Potential Beneficial Effects of Vitamin D in Coronary Artery Disease
por: Legarth, Christian, et al.
Publicado: (2019)

Fighting Thyroid Cancer with Microgravity Research
por: Krüger, Marcus, et al.
Publicado: (2019)

Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity
por: Buken, Christoph, et al.
Publicado: (2019)

Role of Apoptosis in Wound Healing and Apoptosis Alterations in Microgravity
por: Riwaldt, Stefan, et al.
Publicado: (2021)

Multikinase Inhibitor Treatment in Thyroid Cancer
por: Ancker, Ole Vincent, et al.
Publicado: (2019)

Bioactive Candy: Effects of Licorice on the Cardiovascular System
por: Deutch, Mikkel R., et al.
Publicado: (2019)

Tissue Engineering of Cartilage Using a Random Positioning Machine
por: Wehland, Markus, et al.
Publicado: (2020)

Prolonged Exposure to Simulated Microgravity Changes Release of Small Extracellular Vesicle in Breast Cancer Cells
por: Wise, Petra M., et al.
Publicado: (2022)

SARS‐CoV‐2 and hypertension
por: Ravichandran, Briyanth, et al.
Publicado: (2021)

Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2019)

Kinase-Inhibitors in Iodine-Refractory Differentiated Thyroid Cancer—Focus on Occurrence, Mechanisms, and Management of Treatment-Related Hypertension
por: Kaae, Anne Christine, et al.
Publicado: (2021)

Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells
por: Nassef, Mohamed Zakaria, et al.
Publicado: (2019)

The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model
por: Grimm, Daniela, et al.
Publicado: (2022)

Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1
por: Warnke, Elisabeth, et al.
Publicado: (2014)

Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine
por: Bauer, Johann, et al.
Publicado: (2017)

The Effect of Continuous Positive Airway Pressure Therapy on Obstructive Sleep Apnea-Related Hypertension
por: Baran, Ronni, et al.
Publicado: (2021)

Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells
por: Hybel, Trine Engelbrecht, et al.
Publicado: (2020)

Drug-Induced Hypertension Caused by Multikinase Inhibitors (Sorafenib, Sunitinib, Lenvatinib and Axitinib) in Renal Cell Carcinoma Treatment
por: Bæk Møller, Nanna, et al.
Publicado: (2019)

Three-Dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity
por: Dietrichs, Dorothea, et al.
Publicado: (2022)

Changes in Human Foetal Osteoblasts Exposed to the Random Positioning Machine and Bone Construct Tissue Engineering
por: Mann, Vivek, et al.
Publicado: (2019)

Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension
por: Milling, Rikke Vilsbøll, et al.
Publicado: (2018)

Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine
por: Kopp, Sascha, et al.
Publicado: (2016)

Semantic Analysis of Posttranslational Modification of Proteins Accumulated in Thyroid Cancer Cells Exposed to Simulated Microgravity
por: Bauer, Johann, et al.
Publicado: (2018)

Myconanotechnology in veterinary sector: Status quo and future perspectives
por: Hanafy, Mai Hamed
Publicado: (2018)

Microgravity Affects Thyroid Cancer Cells during the TEXUS-53 Mission Stronger than Hypergravity
por: Kopp, Sascha, et al.
Publicado: (2018)

Cancer Studies under Space Conditions: Finding Answers Abroad
por: Cortés-Sánchez, José Luis, et al.
Publicado: (2021)

Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space
por: Wise, Petra M., et al.
Publicado: (2021)

Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space
por: Wise, Petra M., et al.
Publicado: (2021)

Biomarkers for Anti-Angiogenic Therapy in Cancer
por: Wehland, Markus, et al.
Publicado: (2013)

The Adverse Effect of Hypertension in the Treatment of Thyroid Cancer with Multi-Kinase Inhibitors
por: Ancker, Ole Vincent, et al.
Publicado: (2017)

Hypertension Caused by Lenvatinib and Everolimus in the Treatment of Metastatic Renal Cell Carcinoma
por: Bendtsen, Mathias Alrø Fichtner, et al.
Publicado: (2017)

Biomarkers in Metastatic Colorectal Cancer: Status Quo and Future Perspective
por: Puccini, Alberto, et al.
Publicado: (2022)

Microgravity-Related Changes in Bone Density and Treatment Options: A Systematic Review
por: Baran, Ronni, et al.
Publicado: (2022)

Endothelin Receptors and Their Antagonists()()
por: Maguire, Janet J., et al.
Publicado: (2015)

Insight in Adhesion Protein Sialylation and Microgravity Dependent Cell Adhesion—An Omics Network Approach
por: Bauer, Thomas J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dgia79vck1a83sg586ulkg19cl