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Cognition in Children with Arachnoid Cysts

Background: This study aims to evaluate if children with temporal arachnoid cysts (AC) have cognitive symptoms and if neurosurgery improves these. Methods: A prospective case series study including consecutive pediatric patients with temporal AC. The children underwent neuroradiology, neuroopthalmol...

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Autores principales: Sandvik, Ulrika, Adolfsson, Tomas, Jacobson, Dan N., Tedroff, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141502/
https://www.ncbi.nlm.nih.gov/pubmed/32244990
http://dx.doi.org/10.3390/jcm9030850
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author Sandvik, Ulrika
Adolfsson, Tomas
Jacobson, Dan N.
Tedroff, Kristina
author_facet Sandvik, Ulrika
Adolfsson, Tomas
Jacobson, Dan N.
Tedroff, Kristina
author_sort Sandvik, Ulrika
collection PubMed
description Background: This study aims to evaluate if children with temporal arachnoid cysts (AC) have cognitive symptoms and if neurosurgery improves these. Methods: A prospective case series study including consecutive pediatric patients with temporal AC. The children underwent neuroradiology, neuroopthalmologic evaluation, and a standard electroencephalography (EEG). Additionally, a neuropsychologist performed a standardized set of evaluations, with a one-year follow-up consisting of Weschler Intelligence Scale for Children version IV (WISC-IV), FAS (for verbal fluency), Boston Naming Test (BNT, for visual naming ability) and NEPSY-II (Developmental NEuroPSYchological Assessment) for verbal memory. Results: Fifteen children, 9 boys and 6 girls, were evaluated and 11 underwent surgery. The Full Scale IQ subscore (FSIQ) improved from M = 84.8 to M = 93.0 (p = 0.005). The preoperative Verbal Comprehension Index (VCI) was in the low average range (M = 86.7), improving to a level within the average range (M = 94.7, p = 0.001). Preoperative Perceptual Speed Index (PSI) was in the below average range (M = 81.5), improving to a level within the average range (M = 92.5, p = 0.004). Conclusion: ACs are a common finding in a pediatric neurosurgical setting. Our data suggest that some temporal AC have a negative effect on general cognitive ability and that this impairment can be improved by surgery. We suggest a standardized evaluation, including comprehensive and validated neuropsychological assessment tools, to thoroughly assess symptoms as well as the postoperative outcome.
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spelling pubmed-71415022020-04-15 Cognition in Children with Arachnoid Cysts Sandvik, Ulrika Adolfsson, Tomas Jacobson, Dan N. Tedroff, Kristina J Clin Med Article Background: This study aims to evaluate if children with temporal arachnoid cysts (AC) have cognitive symptoms and if neurosurgery improves these. Methods: A prospective case series study including consecutive pediatric patients with temporal AC. The children underwent neuroradiology, neuroopthalmologic evaluation, and a standard electroencephalography (EEG). Additionally, a neuropsychologist performed a standardized set of evaluations, with a one-year follow-up consisting of Weschler Intelligence Scale for Children version IV (WISC-IV), FAS (for verbal fluency), Boston Naming Test (BNT, for visual naming ability) and NEPSY-II (Developmental NEuroPSYchological Assessment) for verbal memory. Results: Fifteen children, 9 boys and 6 girls, were evaluated and 11 underwent surgery. The Full Scale IQ subscore (FSIQ) improved from M = 84.8 to M = 93.0 (p = 0.005). The preoperative Verbal Comprehension Index (VCI) was in the low average range (M = 86.7), improving to a level within the average range (M = 94.7, p = 0.001). Preoperative Perceptual Speed Index (PSI) was in the below average range (M = 81.5), improving to a level within the average range (M = 92.5, p = 0.004). Conclusion: ACs are a common finding in a pediatric neurosurgical setting. Our data suggest that some temporal AC have a negative effect on general cognitive ability and that this impairment can be improved by surgery. We suggest a standardized evaluation, including comprehensive and validated neuropsychological assessment tools, to thoroughly assess symptoms as well as the postoperative outcome. MDPI 2020-03-20 /pmc/articles/PMC7141502/ /pubmed/32244990 http://dx.doi.org/10.3390/jcm9030850 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sandvik, Ulrika
Adolfsson, Tomas
Jacobson, Dan N.
Tedroff, Kristina
Cognition in Children with Arachnoid Cysts
title Cognition in Children with Arachnoid Cysts
title_full Cognition in Children with Arachnoid Cysts
title_fullStr Cognition in Children with Arachnoid Cysts
title_full_unstemmed Cognition in Children with Arachnoid Cysts
title_short Cognition in Children with Arachnoid Cysts
title_sort cognition in children with arachnoid cysts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141502/
https://www.ncbi.nlm.nih.gov/pubmed/32244990
http://dx.doi.org/10.3390/jcm9030850
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