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High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis

Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patient...

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Autores principales: Rosier, Laurent, Zouaghi, Amir, Barré, Valentin, Martins, Raphaël, Probst, Vincent, Marijon, Eloi, Sadoul, Nicolas, Chauveau, Samuel, Da Costa, Antoine, Badoz, Marc, Peyrol, Michael, Barraud, Jérémie, Massoullie, Grégoire, Eschalier, Romain, Espinosa, Madeline, Lesaffre, François, Garcia, Rodrigue, Degand, Bruno, Noël, Antoine, Mansourati, Jacques, Extramiana, Fabrice, Algalarrondo, Vincent, Devilliers, Hervé, Cottin, Yves, Gandjbakhch, Estelle, Guenancia, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141537/
https://www.ncbi.nlm.nih.gov/pubmed/32244983
http://dx.doi.org/10.3390/jcm9030848
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author Rosier, Laurent
Zouaghi, Amir
Barré, Valentin
Martins, Raphaël
Probst, Vincent
Marijon, Eloi
Sadoul, Nicolas
Chauveau, Samuel
Da Costa, Antoine
Badoz, Marc
Peyrol, Michael
Barraud, Jérémie
Massoullie, Grégoire
Eschalier, Romain
Espinosa, Madeline
Lesaffre, François
Garcia, Rodrigue
Degand, Bruno
Noël, Antoine
Mansourati, Jacques
Extramiana, Fabrice
Algalarrondo, Vincent
Devilliers, Hervé
Cottin, Yves
Gandjbakhch, Estelle
Guenancia, Charles
author_facet Rosier, Laurent
Zouaghi, Amir
Barré, Valentin
Martins, Raphaël
Probst, Vincent
Marijon, Eloi
Sadoul, Nicolas
Chauveau, Samuel
Da Costa, Antoine
Badoz, Marc
Peyrol, Michael
Barraud, Jérémie
Massoullie, Grégoire
Eschalier, Romain
Espinosa, Madeline
Lesaffre, François
Garcia, Rodrigue
Degand, Bruno
Noël, Antoine
Mansourati, Jacques
Extramiana, Fabrice
Algalarrondo, Vincent
Devilliers, Hervé
Cottin, Yves
Gandjbakhch, Estelle
Guenancia, Charles
author_sort Rosier, Laurent
collection PubMed
description Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan–Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode.
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spelling pubmed-71415372020-04-15 High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis Rosier, Laurent Zouaghi, Amir Barré, Valentin Martins, Raphaël Probst, Vincent Marijon, Eloi Sadoul, Nicolas Chauveau, Samuel Da Costa, Antoine Badoz, Marc Peyrol, Michael Barraud, Jérémie Massoullie, Grégoire Eschalier, Romain Espinosa, Madeline Lesaffre, François Garcia, Rodrigue Degand, Bruno Noël, Antoine Mansourati, Jacques Extramiana, Fabrice Algalarrondo, Vincent Devilliers, Hervé Cottin, Yves Gandjbakhch, Estelle Guenancia, Charles J Clin Med Article Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan–Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode. MDPI 2020-03-20 /pmc/articles/PMC7141537/ /pubmed/32244983 http://dx.doi.org/10.3390/jcm9030848 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rosier, Laurent
Zouaghi, Amir
Barré, Valentin
Martins, Raphaël
Probst, Vincent
Marijon, Eloi
Sadoul, Nicolas
Chauveau, Samuel
Da Costa, Antoine
Badoz, Marc
Peyrol, Michael
Barraud, Jérémie
Massoullie, Grégoire
Eschalier, Romain
Espinosa, Madeline
Lesaffre, François
Garcia, Rodrigue
Degand, Bruno
Noël, Antoine
Mansourati, Jacques
Extramiana, Fabrice
Algalarrondo, Vincent
Devilliers, Hervé
Cottin, Yves
Gandjbakhch, Estelle
Guenancia, Charles
High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title_full High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title_fullStr High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title_full_unstemmed High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title_short High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
title_sort high risk of sustained ventricular arrhythmia recurrence after acute myocarditis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141537/
https://www.ncbi.nlm.nih.gov/pubmed/32244983
http://dx.doi.org/10.3390/jcm9030848
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