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Novel IL-12 family members shed light on the orchestration of Th1 responses
Interleukin-12 (IL-12), which is composed of a p35 and a p40 subunit, is a proinflammatory natural-killer (NK) cell-stimulating, Th1-inducing and Th1-maintaining cytokine, which promotes cell-mediated immunity. On activation, heterodimeric IL-12 is found in small amounts, whereas free p40 is produce...
Autores principales: | Brombacher, Frank, Kastelein, Robert A., Alber, Gottfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd.
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141566/ https://www.ncbi.nlm.nih.gov/pubmed/12697453 http://dx.doi.org/10.1016/S1471-4906(03)00067-X |
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