Route of inoculation and mosquito vector exposure modulate dengue virus replication kinetics and immune responses in rhesus macaques

Dengue virus (DENV) is transmitted by infectious mosquitoes during blood-feeding via saliva containing biologically-active proteins. Here, we examined the effect of varying DENV infection modality in rhesus macaques in order to improve the DENV nonhuman primate (NHP) challenge model. NHPs were expos...

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Detalles Bibliográficos
Autores principales: McCracken, Michael K., Gromowski, Gregory D., Garver, Lindsey S., Goupil, Brad A., Walker, Kathryne D., Friberg, Heather, Currier, Jeffrey R., Rutvisuttinunt, Wiriya, Hinton, Kevin L., Christofferson, Rebecca C., Mores, Christopher N., Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Thomas, Stephen J., Jarman, Richard G., Vaughn, David W., Putnak, J. Robert, Warter, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141610/
https://www.ncbi.nlm.nih.gov/pubmed/32267846
http://dx.doi.org/10.1371/journal.pntd.0008191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141610/
https://www.ncbi.nlm.nih.gov/pubmed/32267846
http://dx.doi.org/10.1371/journal.pntd.0008191

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