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Correlation between blood telomere length and CD4+ CD8+ T-cell subsets changes 96 weeks after initiation of antiretroviral therapy in HIV-1–positive individuals

In 31 participants who started first-line antiretroviral therapy in the NEAT 001/ANRS 143 clinical trial, we found after 96 weeks a statistically significant increase in blood telomere length (TL) of 0.04 (T/S Ratio) (p = 0.03). This increase was positively correlated with both the change in the per...

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Detalles Bibliográficos
Autores principales: Chalouni, Mathieu, Rodriguez-Centeno, Javier, Samri, Assia, Blanco, Julian, Stella-Ascariz, Natalia, Wallet, Cedrick, Knobel, Hernando, Zucman, David, Alejos Ferreras, Belen, Autran, Brigitte, Thiebaut, Rodolphe, Raffi, François, Arribas, Jose Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141657/
https://www.ncbi.nlm.nih.gov/pubmed/32267847
http://dx.doi.org/10.1371/journal.pone.0230772