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The pharyngeal nervous system orchestrates feeding behavior in planarians

Planarians exhibit traits of cephalization but are unique among bilaterians in that they ingest food by means of goal-directed movements of a trunk-positioned pharynx, following protrusion of the pharynx out of the body, raising the question of how planarians control such a complex set of body movem...

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Autores principales: Miyamoto, Mai, Hattori, Miki, Hosoda, Kazutaka, Sawamoto, Mika, Motoishi, Minako, Hayashi, Tetsutaro, Inoue, Takeshi, Umesono, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141820/
https://www.ncbi.nlm.nih.gov/pubmed/32285000
http://dx.doi.org/10.1126/sciadv.aaz0882
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author Miyamoto, Mai
Hattori, Miki
Hosoda, Kazutaka
Sawamoto, Mika
Motoishi, Minako
Hayashi, Tetsutaro
Inoue, Takeshi
Umesono, Yoshihiko
author_facet Miyamoto, Mai
Hattori, Miki
Hosoda, Kazutaka
Sawamoto, Mika
Motoishi, Minako
Hayashi, Tetsutaro
Inoue, Takeshi
Umesono, Yoshihiko
author_sort Miyamoto, Mai
collection PubMed
description Planarians exhibit traits of cephalization but are unique among bilaterians in that they ingest food by means of goal-directed movements of a trunk-positioned pharynx, following protrusion of the pharynx out of the body, raising the question of how planarians control such a complex set of body movements for achieving robust feeding. Here, we use the freshwater planarian Dugesia japonica to show that an isolated pharynx amputated from the planarian body self-directedly executes its entire sequence of feeding functions: food sensing, approach, decisions about ingestion, and intake. Gene-specific silencing experiments by RNA interference demonstrated that the pharyngeal nervous system (PhNS) is required not only for feeding functions of the pharynx itself but also for food-localization movements of individual animals, presumably via communication with the brain. These findings reveal an unexpected central role of the PhNS in the linkage between unique morphological phenotypes and feeding behavior in planarians.
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spelling pubmed-71418202020-04-13 The pharyngeal nervous system orchestrates feeding behavior in planarians Miyamoto, Mai Hattori, Miki Hosoda, Kazutaka Sawamoto, Mika Motoishi, Minako Hayashi, Tetsutaro Inoue, Takeshi Umesono, Yoshihiko Sci Adv Research Articles Planarians exhibit traits of cephalization but are unique among bilaterians in that they ingest food by means of goal-directed movements of a trunk-positioned pharynx, following protrusion of the pharynx out of the body, raising the question of how planarians control such a complex set of body movements for achieving robust feeding. Here, we use the freshwater planarian Dugesia japonica to show that an isolated pharynx amputated from the planarian body self-directedly executes its entire sequence of feeding functions: food sensing, approach, decisions about ingestion, and intake. Gene-specific silencing experiments by RNA interference demonstrated that the pharyngeal nervous system (PhNS) is required not only for feeding functions of the pharynx itself but also for food-localization movements of individual animals, presumably via communication with the brain. These findings reveal an unexpected central role of the PhNS in the linkage between unique morphological phenotypes and feeding behavior in planarians. American Association for the Advancement of Science 2020-04-08 /pmc/articles/PMC7141820/ /pubmed/32285000 http://dx.doi.org/10.1126/sciadv.aaz0882 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Research Articles
Miyamoto, Mai
Hattori, Miki
Hosoda, Kazutaka
Sawamoto, Mika
Motoishi, Minako
Hayashi, Tetsutaro
Inoue, Takeshi
Umesono, Yoshihiko
The pharyngeal nervous system orchestrates feeding behavior in planarians
title The pharyngeal nervous system orchestrates feeding behavior in planarians
title_full The pharyngeal nervous system orchestrates feeding behavior in planarians
title_fullStr The pharyngeal nervous system orchestrates feeding behavior in planarians
title_full_unstemmed The pharyngeal nervous system orchestrates feeding behavior in planarians
title_short The pharyngeal nervous system orchestrates feeding behavior in planarians
title_sort pharyngeal nervous system orchestrates feeding behavior in planarians
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141820/
https://www.ncbi.nlm.nih.gov/pubmed/32285000
http://dx.doi.org/10.1126/sciadv.aaz0882
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