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Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking

Mesenchymal stromal cells (MSCs) modulate immune cells to ameliorate multiple inflammatory pathologies. Biophysical signals that regulate this process are poorly defined. By engineering hydrogels with tunable biophysical parameters relevant to bone marrow where MSCs naturally reside, we show that so...

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Detalles Bibliográficos
Autores principales:	Wong, Sing Wan, Lenzini, Stephen, Cooper, Madeline H., Mooney, David J., Shin, Jae-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141831/ https://www.ncbi.nlm.nih.gov/pubmed/32284989 http://dx.doi.org/10.1126/sciadv.aaw0158

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