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dSreg: a Bayesian model to integrate changes in splicing and RNA-binding protein activity

MOTIVATION: Alternative splicing (AS) is an important mechanism in the generation of transcript diversity across mammals. AS patterns are dynamically regulated during development and in response to environmental changes. Defects or perturbations in its regulation may lead to cancer or neurological d...

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Detalles Bibliográficos
Autores principales: Martí-Gómez, Carlos, Lara-Pezzi, Enrique, Sánchez-Cabo, Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141860/
https://www.ncbi.nlm.nih.gov/pubmed/31834368
http://dx.doi.org/10.1093/bioinformatics/btz915

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