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dSreg: a Bayesian model to integrate changes in splicing and RNA-binding protein activity
MOTIVATION: Alternative splicing (AS) is an important mechanism in the generation of transcript diversity across mammals. AS patterns are dynamically regulated during development and in response to environmental changes. Defects or perturbations in its regulation may lead to cancer or neurological d...
Autores principales: | Martí-Gómez, Carlos, Lara-Pezzi, Enrique, Sánchez-Cabo, Fátima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141860/ https://www.ncbi.nlm.nih.gov/pubmed/31834368 http://dx.doi.org/10.1093/bioinformatics/btz915 |
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